MacIRSSI sysctl.co.uk

Irssi, done the Mac way

All the features that you know and love from Irssi on Linux (or command line OS X) but with added juice from OS X. MacIrssi will automatically disconnect and reconnect your active connections when you put your Mac to sleep.

/connect irc.freenode.net
/join #room

Agaric looking for and not finding: macirssi perl script growl notification all messages in chat room